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Differential effects of microenvironmentally presented interleukin 3 versus soluble growth factor on primitive human hematopoietic cells.

The effect of IL-3 on hematopoiesis in long-term culture (LTC) was studied by cocultivating normal human marrow cells with human marrow fibroblast feeders engineered to constitutively produce IL-3 and by adding soluble IL-3 to LTC according to a variety of dose-time schedules. Feeders stably produci...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Otsuka, T, Thacker, J D, Eaves, C J, Hogge, D E
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295347/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1864955/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115320
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