Differential effects of microenvironmentally presented interleukin 3 versus soluble growth factor on primitive human hematopoietic cells.

The effect of IL-3 on hematopoiesis in long-term culture (LTC) was studied by cocultivating normal human marrow cells with human marrow fibroblast feeders engineered to constitutively produce IL-3 and by adding soluble IL-3 to LTC according to a variety of dose-time schedules. Feeders stably produci...

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Publié dans:	J Clin Invest
Auteurs principaux:	Otsuka, T, Thacker, J D, Eaves, C J, Hogge, D E
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Clinical Investigation 1991
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295347/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1864955/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115320
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