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Sds22 regulates aurora B activity and microtubule–kinetochore interactions at mitosis

We have studied Sds22, a conserved regulator of protein phosphatase 1 (PP1) activity, and determined its role in modulating the activity of aurora B kinase and kinetochore–microtubule interactions. Sds22 is required for proper progression through mitosis and localization of PP1 to mitotic kinetochor...

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Main Authors: Posch, Markus, Khoudoli, Guennadi A., Swift, Sam, King, Emma M., DeLuca, Jennifer G., Swedlow, Jason R.
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2953433/
https://ncbi.nlm.nih.gov/pubmed/20921135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200912046
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