Acyclovir and Aβ42 peptide attenuates HSV-1-induced miRNA-146a levels in human brain cells

Human brains harbor herpes simplex virus type-1 (HSV-1) DNA which normally remains quiescent throughout many decades of life. HSV-1 is associated with viral encephalopathy and with the amyloid beta 42 (Aβ42) peptide-enriched lesions that characterize Alzheimer’s disease neuropathology. Here we repor...

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Bibliografiske detaljer
Main Authors: Lukiw, WJ, Cui, JG, Li, YY, Bhattacharjee, PS, Corkern, M, Clement, C, Kammerman, EM, Ball, MJ, Zhao, Y, Hill, JM
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2953363/
https://ncbi.nlm.nih.gov/pubmed/20683212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/WNR.0b013e32833da51a
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