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miRNA-155 up-regulation and complement factor H (CFH) deficits in Down’s Syndrome
Down’s syndrome, a congenital disorder associated with cognitive impairment and early onset Alzheimer’s disease, is a progressive genetic pathology resulting from full or partial triplication of chromosome-21. Down’s brain is typified by activated microglia, increases in inflammatory signaling and a...
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| Main Authors: | , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2012
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3264826/ https://ncbi.nlm.nih.gov/pubmed/22182977 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/WNR.0b013e32834f4eb4 |
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