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miRNA-155 up-regulation and complement factor H (CFH) deficits in Down’s Syndrome

Down’s syndrome, a congenital disorder associated with cognitive impairment and early onset Alzheimer’s disease, is a progressive genetic pathology resulting from full or partial triplication of chromosome-21. Down’s brain is typified by activated microglia, increases in inflammatory signaling and a...

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Autors principals: Li, YY, Alexandrov, PN, Pogue, AI, Zhao, Y, Bhattacharjee, S, Lukiw, WJ
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3264826/
https://ncbi.nlm.nih.gov/pubmed/22182977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/WNR.0b013e32834f4eb4
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