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Arg60 to Leu mutation of the human thromboxane A2 receptor in a dominantly inherited bleeding disorder.

Recent advances in molecular genetics have revealed the mechanisms underlying a variety of inherited human disorders. Among them, mutations in G protein-coupled receptors have clearly demonstrated two types of abnormalities, namely loss of function and constitutive activation of the receptors. Throm...

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Detalles Bibliográficos
Main Authors: Hirata, T, Kakizuka, A, Ushikubi, F, Fuse, I, Okuma, M, Narumiya, S
Formato: Artigo
Idioma:Inglês
Publicado: 1994
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC295328/
https://ncbi.nlm.nih.gov/pubmed/7929844
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