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Characterization of an autosomal dominant bleeding disorder caused by a thrombomodulin mutation

We describe a family with an autosomal dominant disorder characterized by severe trauma- and surgery-related bleeding. The proband, who experienced life-threatening bleeding during a routine operation, had normal clotting times, but markedly reduced prothrombin consumption. Plasma levels of all coag...

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書目詳細資料
發表在:Blood
Main Authors: Dargaud, Yesim, Scoazec, Jean Yves, Wielders, Simone J. H., Trzeciak, Christine, Hackeng, Tilman M., Négrier, Claude, Hemker, H. Coenraad, Lindhout, Theo, Castoldi, Elisabetta
格式: Artigo
語言:Inglês
出版: American Society of Hematology 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4342361/
https://ncbi.nlm.nih.gov/pubmed/25564403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-10-604553
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