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Characterization of an autosomal dominant bleeding disorder caused by a thrombomodulin mutation
We describe a family with an autosomal dominant disorder characterized by severe trauma- and surgery-related bleeding. The proband, who experienced life-threatening bleeding during a routine operation, had normal clotting times, but markedly reduced prothrombin consumption. Plasma levels of all coag...
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| 發表在: | Blood |
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| Main Authors: | , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society of Hematology
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4342361/ https://ncbi.nlm.nih.gov/pubmed/25564403 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-10-604553 |
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