Protein 4.1 deficiency associated with an altered binding to the spectrin-actin complex of the red cell membrane skeleton.

Protein 4.1 has been defined as a major component of the subcortical skeleton of erythrocytes. It binds the spectrin--actin scaffold through a 10-kD internal domain. This binding requires an essential 21-amino acid sequence motif, Motif I, which is retained by alternative splicing at the late stage...

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Publicado en:	J Clin Invest
Autores principales:	Lorenzo, F, Dalla Venezia, N, Morlé, L, Baklouti, F, Alloisio, N, Ducluzeau, M T, Roda, L, Lefrançois, P, Delaunay, J
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Clinical Investigation 1994
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295326/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7929842/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117508
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