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The ESEV PDZ-Binding Motif of the Avian Influenza A Virus NS1 Protein Protects Infected Cells from Apoptosis by Directly Targeting Scribble

The NS1 protein from influenza A viruses contains a four-amino-acid sequence at its carboxyl terminus that is termed the PDZ-binding motif (PBM). The NS1 PBM is predicted to bind to cellular PDZ proteins and functions as a virulence determinant in infected mice. ESEV is the consensus PBM sequence of...

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Main Authors: Liu, Hongbing, Golebiewski, Lisa, Dow, Eugene C., Krug, Robert M., Javier, Ronald T., Rice, Andrew P.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2953166/
https://ncbi.nlm.nih.gov/pubmed/20702615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01278-10
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