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Poxvirus Complement Control Proteins Are Expressed on the Cell Surface through an Intermolecular Disulfide Bridge with the Viral A56 Protein

The vaccinia virus (VACV) complement control protein (VCP) is an immunomodulatory protein that is both secreted from and expressed on the surface of infected cells. Surface expression of VCP occurs though an interaction with the viral transmembrane protein A56 and is dependent on a free N-terminal c...

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Bibliografiske detaljer
Main Authors: DeHaven, Brian C., Girgis, Natasha M., Xiao, Yuhong, Hudson, Paul N., Olson, Victoria A., Damon, Inger K., Isaacs, Stuart N.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2953161/
https://ncbi.nlm.nih.gov/pubmed/20719953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00372-10
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