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Complete pathway for protein disulfide bond formation encoded by poxviruses
We show that three cytoplasmic thiol oxidoreductases encoded by vaccinia virus comprise a complete pathway for formation of disulfide bonds in intracellular virion membrane proteins. The pathway was defined by analyzing conditional lethal mutants and effects of cysteine to serine substitutions and b...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The National Academy of Sciences
2002
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC124460/ https://ncbi.nlm.nih.gov/pubmed/11983854 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.062163799 |
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