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Complete pathway for protein disulfide bond formation encoded by poxviruses

We show that three cytoplasmic thiol oxidoreductases encoded by vaccinia virus comprise a complete pathway for formation of disulfide bonds in intracellular virion membrane proteins. The pathway was defined by analyzing conditional lethal mutants and effects of cysteine to serine substitutions and b...

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Bibliografiske detaljer
Main Authors: Senkevich, Tatiana G., White, Christine L., Koonin, Eugene V., Moss, Bernard
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 2002
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC124460/
https://ncbi.nlm.nih.gov/pubmed/11983854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.062163799
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