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The Noncanonical Gag Domains p8 and n Are Critical for Assembly and Release of Mouse Mammary Tumor Virus

The mouse mammary tumor virus (MMTV) Gag contains the unique domains pp21, p3, p8, and n. We investigated the contribution of these domains to particle assembly and found that the region spanning the p8 and n domains is critical for shape determination and assembly. Deletion of pp21 and p3 reduced t...

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Détails bibliographiques
Auteurs principaux: Zábranský, Aleš, Hoboth, Peter, Hadravová, Romana, Štokrová, Jitka, Sakalian, Michael, Pichová, Iva
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2010
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2953144/
https://ncbi.nlm.nih.gov/pubmed/20739518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00652-10
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