Thrombocytopenia in Mice Lacking the Carboxy-Terminal Regulatory Domain of the Ets Transcription Factor Fli1

Targeted disruption of the Fli1 gene results in embryonic lethality. To dissect the roles of functional domains in Fli1, we recently generated mutant Fli1 mice that express a truncated Fli1 protein (Fli1(ΔCTA)) that lacks the carboxy-terminal regulatory (CTA) domain. Heterozygous Fli1(Δ)(CTA) mice a...

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Main Authors: Moussa, Omar, LaRue, Amanda C., Abangan, Romeo S., Williams, Christopher R., Zhang, Xian K., Masuya, Masahiro, Gong, Yong Z., Spyropoulos, Demetri D., Ogawa, Makio, Gilkeson, Gary, Watson, Dennis K.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology (ASM) 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2953061/
https://ncbi.nlm.nih.gov/pubmed/20823267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01112-09
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