Thrombocytopenia in Mice Lacking the Carboxy-Terminal Regulatory Domain of the Ets Transcription Factor Fli1

Targeted disruption of the Fli1 gene results in embryonic lethality. To dissect the roles of functional domains in Fli1, we recently generated mutant Fli1 mice that express a truncated Fli1 protein (Fli1(ΔCTA)) that lacks the carboxy-terminal regulatory (CTA) domain. Heterozygous Fli1(Δ)(CTA) mice a...

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Detalhes bibliográficos
Main Authors: Moussa, Omar, LaRue, Amanda C., Abangan, Romeo S., Williams, Christopher R., Zhang, Xian K., Masuya, Masahiro, Gong, Yong Z., Spyropoulos, Demetri D., Ogawa, Makio, Gilkeson, Gary, Watson, Dennis K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2953061/
https://ncbi.nlm.nih.gov/pubmed/20823267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01112-09
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