Error-Prone Translesion DNA Synthesis by Escherichia coli DNA Polymerase IV (DinB) on Templates Containing 1,2-dihydro-2-oxoadenine

Escherichia coli DNA polymerase IV (Pol IV) is involved in bypass replication of damaged bases in DNA. Reactive oxygen species (ROS) are generated continuously during normal metabolism and as a result of exogenous stress such as ionizing radiation. ROS induce various kinds of base damage in DNA. It...

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Main Authors: Hori, Masaki, Yonekura, Shin-Ichiro, Nohmi, Takehiko, Gruz, Petr, Sugiyama, Hiroshi, Yonei, Shuji, Zhang-Akiyama, Qiu-Mei
Formato: Artigo
Idioma:Inglês
Publicado: SAGE-Hindawi Access to Research 2010
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2952919/
https://ncbi.nlm.nih.gov/pubmed/20976264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2010/807579
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