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Protein evolution in yeast transcription factor subnetworks

When averaged over the full yeast protein–protein interaction and transcriptional regulatory networks, protein hubs with many interaction partners or regulators tend to evolve significantly more slowly due to increased negative selection. However, genome-wide analysis of protein evolution in the sub...

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Detalhes bibliográficos
Main Authors: Wang, Yong, Franzosa, Eric A., Zhang, Xiang-Sun, Xia, Yu
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2952844/
https://ncbi.nlm.nih.gov/pubmed/20466810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq353
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