Smoking, DNA Adducts and Number of Risk DNA Repair Alleles in Lung Cancer Cases, in Subjects with Benign Lung Diseases and in Controls

Smoke constituents can induce DNA adducts that cause mutations and lead to lung cancer. We have analyzed DNA adducts and polymorphisms in two DNA repair genes, for example, XRCC1 Arg194Trp and Arg399Gln genes and XRCC3 Thr241Met gene, in 34 lung cancer cases in respect to 30 subjects with benign lun...

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Detalhes bibliográficos
Main Authors: Peluso, Marco, Munnia, Armelle, Piro, Sara, Armillis, Alessandra, Ceppi, Marcello, Matullo, Giuseppe, Puntoni, Riccardo
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE-Hindawi Access to Research 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2952824/
https://ncbi.nlm.nih.gov/pubmed/20976253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2010/386798
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