Aberrant Methylation of Hypermethylated-in-Cancer-1 and Exocyclic DNA Adducts in Tobacco Smokers

Tobacco smoke has been shown to produce both DNA damage and epigenetic alterations. However, the potential role of DNA damage in generating epigenetic changes is largely underinvestigated in human studies. We examined the effects of smoking on the levels of DNA methylation in genes for tumor protein...

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Main Authors: Peluso, Marco E. M., Munnia, Armelle, Bollati, Valentina, Srivatanakul, Petcharin, Jedpiyawongse, Adisorn, Sangrajrang, Suleeporn, Ceppi, Marcello, Giese, Roger W., Boffetta, Paolo, Baccarelli, Andrea A.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3871933/
https://ncbi.nlm.nih.gov/pubmed/24154486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kft241
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