Insights into the Structures of DNA Damaged by Hydroxyl Radical: Crystal Structures of DNA Duplexes Containing 5-Formyluracil

Hydroxyl radicals are potent mutagens that attack DNA to form various base and ribose derivatives. One of the major damaged thymine derivatives is 5-formyluracil (fU), which induces pyrimidine transition during replication. In order to establish the structural basis for such mutagenesis, the crystal...

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Autores principales: Tsunoda, Masaru, Sakaue, Takeshi, Naito, Satoko, Sunami, Tomoko, Abe, Naoko, Ueno, Yoshihito, Matsuda, Akira, Takénaka, Akio
Formato: Artigo
Lenguaje:Inglês
Publicado: SAGE-Hindawi Access to Research 2010
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2952808/
https://ncbi.nlm.nih.gov/pubmed/20976303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2010/107289
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