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Antimicrobial breakpoints for Gram-negative aerobic bacteria based on pharmacokinetic – pharmacodynamic models with Monte Carlo simulation
OBJECTIVES: This study describes a comprehensive programme designed to develop pharmacokinetic–pharmacodynamic (PK–PD) breakpoints for numerous antimicrobial classes against key Gram-negative aerobic bacteria. METHODS: A 10 000 subject Monte Carlo simulation was constructed for 13 antimicrobials (21...
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| Glavni autori: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2008
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2952740/ https://ncbi.nlm.nih.gov/pubmed/18252694 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkm536 |
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