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Recombinant Bacterial Expression and Purification of Human Fragile X Mental Retardation Protein Isoform 1

The loss of expression of the fragile X mental retardation protein (FMRP) leads to fragile X syndrome. FMRP has two types of RNA binding domains, two K-homology domains and an arginine-glycine-glycine box domain, and it is propose to act as a translation regulator of specific messenger RNA. The inte...

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Detalhes bibliográficos
Main Authors: Evans, Timothy L., Mihailescu, Mihaela-Rita
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2952666/
https://ncbi.nlm.nih.gov/pubmed/20541608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pep.2010.06.002
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