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The Role of Fragile X Mental Retardation Protein in Major Mental Disorders

Fragile X mental retardation protein (FMRP) is highly enriched in neurons and binds to approximately 4% of mRNAs in mammalian brain. Its loss is a hallmark of fragile X syndrome (FXS), the most common form of mental retardation. In this review we discuss the mutation in the fragile X mental retardat...

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Hlavní autoři: Fatemi, S. Hossein, Folsom, Timothy D.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3078953/
https://ncbi.nlm.nih.gov/pubmed/21108954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2010.11.011
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