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Structure of the MADS-box/MEF2 Domain of MEF2A Bound to DNA and Its Implication for Myocardin Recruitment

Myocyte enhancer factor 2 (MEF2) regulates specific gene expression in diverse developmental programs and adaptive responses. MEF2 recognizes DNA and interacts with transcription cofactors through a highly conserved N-terminal domain referred to as the MADS-box/MEF2 domain. Here we present the cryst...

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Bibliographic Details
Main Authors: Wu, Yongqing, Dey, Raja, Han, Aidong, Jayathilaka, Nimanthi, Philips, Michael, Ye, Jun, Chen, Lin
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2952653/
https://ncbi.nlm.nih.gov/pubmed/20132824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.01.067
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