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Inhibition of the Nuclear Factor-κB Pathway Prevents Beta Cell Failure and Diet Induced Diabetes in Psammomys obesus

BACKGROUND: High doses of anti-inflammatory drugs, such as aspirin and salicylates, improve glucose metabolism in insulin resistant and type 2 diabetic patients. It has also been shown that the glucose lowering effect is related to the unspecific ability of these drugs to inhibit inhibitor kinaseβ (...

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Autori principali: Friberg, Josefine, Tonnesen, Morten F., Heller, Schott, Pociot, Flemming, Bödvarsdottir, Thóra B., Karlsen, Allan E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2952629/
https://ncbi.nlm.nih.gov/pubmed/20948968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013341
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