Treatment with a proton pump inhibitor improves glycaemic control in Psammomys obesus, a model of type 2 diabetes

AIMS/HYPOTHESIS: Gastrin has been implicated in islet growth/neogenesis, and proton pump inhibitors (PPIs) have been shown to increase endogenous gastrin levels in animals and humans. Therefore, we investigated the effect of PPIs in a model of type 2 diabetes, Psammomys obesus. METHODS: P. obesus (m...

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Huvudupphovsmän: Bödvarsdóttir, T. B., Hove, K. D., Gotfredsen, C. F., Pridal, L., Vaag, A., Karlsen, A. E., Petersen, J. S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Springer-Verlag 2010
Ämnen:
Short Communication
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2931641/
https://ncbi.nlm.nih.gov/pubmed/20585936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-010-1825-6
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