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Insights on Glucocorticoid Receptor Activity Modulation through the Binding of Rigid Steroids

BACKGROUND: The glucocorticoid receptor (GR) is a transcription factor that regulates gene expression in a ligand-dependent fashion. This modular protein is one of the major pharmacological targets due to its involvement in both cause and treatment of many human diseases. Intense efforts have been m...

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Detalhes bibliográficos
Main Authors: Presman, Diego M., Alvarez, Lautaro D., Levi, Valeria, Eduardo, Silvina, Digman, Michelle A., Martí, Marcelo A., Veleiro, Adriana S., Burton, Gerardo, Pecci, Adali
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2952596/
https://ncbi.nlm.nih.gov/pubmed/20949009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013279
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