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Insights on Glucocorticoid Receptor Activity Modulation through the Binding of Rigid Steroids
BACKGROUND: The glucocorticoid receptor (GR) is a transcription factor that regulates gene expression in a ligand-dependent fashion. This modular protein is one of the major pharmacological targets due to its involvement in both cause and treatment of many human diseases. Intense efforts have been m...
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Main Authors: | , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2952596/ https://ncbi.nlm.nih.gov/pubmed/20949009 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013279 |
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