Effects of PCSK9 genetic variants on plasma LDL cholesterol levels and risk of premature myocardial infarction in the Italian population

The R46L variant in the proprotein-convertase subtilisin-kexin type 9 (PCSK9) gene was associated with reduced levels of LDL and total cholesterol and with a lower risk of coronary artery disease. We investigated the association of R46L with myocardial infarction (MI) in 1,880 Italian patients with...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Guella, Ilaria, Asselta, Rosanna, Ardissino, Diego, Merlini, Pier Angelica, Peyvandi, Flora, Kathiresan, Sekar, Mannucci, Pier Mannuccio, Tubaro, Marco, Duga, Stefano
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Biochemistry and Molecular Biology 2010
Fag:
Patient-Oriented and Epidemiological Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2952575/
https://ncbi.nlm.nih.gov/pubmed/20699424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M010009
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker