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Chromogranin B regulates calcium signaling, NF-κB activity and BNP production in cardiomyocytes

Altered regulation of signaling pathways can lead to pathologies including cardiac hypertrophy and heart failure (HF). We report that neonatal and adult cardiomyocytes express chromogranin B (CGB), a calcium (Ca(2+)) binding protein which modulates Ca(2+) release by the inositol 1,4,5-trisphosphate...

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Detalhes bibliográficos
Main Authors: Heidrich, Felix M., Zhang, Kun, Estrada, Manuel, Huang, Yan, Giordano, Frank J., Ehrlich, Barbara E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2952358/
https://ncbi.nlm.nih.gov/pubmed/18420944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.107.166033
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