Differential Effects of Ceramide and Sphingosine 1-Phosphate on ERM Phosphorylation: PROBING SPHINGOLIPID SIGNALING AT THE OUTER PLASMA MEMBRANE

ERM proteins are regulated by phosphorylation of the most C-terminal threonine residue, switching them from an activated to an inactivated form. However, little is known about the control of this regulation. Previous work in our group demonstrated that secretion of acid sphingomyelinase acts upstrea...

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Bibliographic Details
Main Authors: Canals, Daniel, Jenkins, Russell W., Roddy, Patrick, Hernández-Corbacho, María José, Obeid, Lina M., Hannun, Yusuf A.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2010
Subjects:
Signal Transduction
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2952249/
https://ncbi.nlm.nih.gov/pubmed/20679347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.141028
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