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Bacterial Pathogen-associated Molecular Patterns Stimulate Biological Activity of Orthopaedic Wear Particles by Activating Cognate Toll-like Receptors

Aseptic loosening of orthopaedic implants is induced by wear particles generated from the polymeric and metallic components of the implants. Substantial evidence suggests that activation of Toll-like receptors (TLRs) may contribute to the biological activity of the wear particles. Although pathogen-...

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Detalhes bibliográficos
Main Authors: Greenfield, Edward M., Beidelschies, Michelle A., Tatro, Joscelyn M., Goldberg, Victor M., Hise, Amy G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2952239/
https://ncbi.nlm.nih.gov/pubmed/20729214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.136895
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