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Titanium particles activate Toll-like Receptor 4 independently of lipid rafts in RAW264.7 murine macrophages
Adherent PAMPs (pathogen-associated molecular patterns) act through Toll-like receptor2 (TLR2) and TLR4 to increase the biological activity of orthopaedic wear particles in cell culture and animal models of implant loosening. This study tested whether this is dependent on TLR association with lipid...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3010285/ https://ncbi.nlm.nih.gov/pubmed/20806319 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jor.21199 |
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