A Novel Pathway for Inducible Nitric-oxide Synthase Activation through Inflammasomes

Innate immune recognition of flagellin is shared by transmembrane TLR5 and cytosolic Nlrc4 (NOD-like receptor family CARD (caspase activation recruitment domain) domain containing 4)/Naip5 (neuronal apoptosis inhibitory protein 5). TLR5 activates inflammatory genes through MYD88 pathway, whereas Nlr...

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Detalhes bibliográficos
Main Authors: Buzzo, Carina L., Campopiano, Julia C., Massis, Liliana M., Lage, Silvia L., Cassado, Alexandra A., Leme-Souza, Rafael, Cunha, Larissa D., Russo, Momtchilo, Zamboni, Dario S., Amarante-Mendes, Gustavo P., Bortoluci, Karina R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2952210/
https://ncbi.nlm.nih.gov/pubmed/20702413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.124297
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