Prototypical anti-inflammatory cytokine IL-10 prevents loss of IGF-I-induced myogenin protein expression caused by IL-1β

Prolonged and excessive inflammation is implicated in resistance to the biological actions of IGF-I and contributes to the pathophysiology of neurodegenerative, metabolic, and muscle-wasting disorders. IL-10 is a critical anti-inflammatory cytokine that restrains inflammatory responses in macrophage...

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Bibliographic Details
Main Authors: Strle, Klemen, McCusker, Robert H., Johnson, Rodney W., Zunich, Samantha M., Dantzer, Robert, Kelley, Keith W.
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2951888/
https://ncbi.nlm.nih.gov/pubmed/18270299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00662.2007
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