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Kismet/CHD7 regulates axon morphology, memory and locomotion in a Drosophila model of CHARGE syndrome
CHARGE syndrome (CS, OMIM #214800) is a rare, autosomal dominant disorder, two-thirds of which are caused by haplo-insufficiency in the Chd7 gene. Here, we show that the Drosophila homolog of Chd7, kismet, is required for proper axonal pruning, guidance and extension in the developing fly's cen...
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| Asıl Yazarlar: | , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Oxford University Press
2010
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2951870/ https://ncbi.nlm.nih.gov/pubmed/20716578 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddq348 |
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