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Nucleotide-resolution analysis of structural variants using BreakSeq and a breakpoint library
Structural variants (SVs) are a major source of human genomic variation; however, characterizing them at nucleotide resolution remains challenging. Here we assemble a library of breakpoints at nucleotide resolution from collating and standardizing ~2,000 published SVs. For each breakpoint, we infer...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2951730/ https://ncbi.nlm.nih.gov/pubmed/20037582 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.1600 |
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