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Analysis of deletion breakpoints from 1,092 humans reveals details of mutation mechanisms

Investigating genomic structural variants at basepair resolution is crucial for understanding their formation mechanisms. We identify and analyze 8,943 deletion breakpoints in 1,092 samples from the 1000 Genomes Project. We find breakpoints have more nearby SNPs and indels than the genomic average,...

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Dettagli Bibliografici
Pubblicato in:Nat Commun
Autori principali: Abyzov, Alexej, Li, Shantao, Kim, Daniel Rhee, Mohiyuddin, Marghoob, Stütz, Adrian M., Parrish, Nicholas F., Mu, Xinmeng Jasmine, Clark, Wyatt, Chen, Ken, Hurles, Matthew, Korbel, Jan O., Lam, Hugo Y. K., Lee, Charles, Gerstein, Mark B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4451611/
https://ncbi.nlm.nih.gov/pubmed/26028266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8256
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