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Checks and Balances: IL-23 in the intestine
In this issue of Immunity, Ahern et al. (2010) show that IL-23R signaling in CD4(+) T cells induces effector and suppresses regulatory CD4(+) T cells, which is critical for the development of intestinal but not systemic inflammation.
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2951684/ https://ncbi.nlm.nih.gov/pubmed/20732638 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2010.08.005 |
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