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The effect of deoxygenation on whole-cell conductance of red blood cells from healthy individuals and patients with sickle cell disease
Red blood cells from patients with sickle cell disease (SCD) exhibit increased electrogenic cation permeability, particularly following deoxygenation and hemoglobin (Hb) polymerisation. This cation permeability, termed P(sickle), contributes to cellular dehydration and sickling, and its inhibition r...
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| Asıl Yazarlar: | , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society of Hematology
2007
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2951509/ https://ncbi.nlm.nih.gov/pubmed/17138828 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-03-001404 |
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