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The effect of deoxygenation on whole-cell conductance of red blood cells from healthy individuals and patients with sickle cell disease
Red blood cells from patients with sickle cell disease (SCD) exhibit increased electrogenic cation permeability, particularly following deoxygenation and hemoglobin (Hb) polymerisation. This cation permeability, termed P(sickle), contributes to cellular dehydration and sickling, and its inhibition r...
Gorde:
| Egile Nagusiak: | , , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
American Society of Hematology
2007
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2951509/ https://ncbi.nlm.nih.gov/pubmed/17138828 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-03-001404 |
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