Viral Replication Rate Regulates Clinical Outcome and CD8 T Cell Responses during Highly Pathogenic H5N1 Influenza Virus Infection in Mice

Since the first recorded infection of humans with H5N1 viruses of avian origin in 1997, sporadic human infections continue to occur with a staggering mortality rate of >60%. Although sustained human-to-human transmission has not occurred yet, there is a growing concern that these H5N1 viruses mig...

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Détails bibliographiques
Auteurs principaux: Hatta, Yasuko, Hershberger, Karen, Shinya, Kyoko, Proll, Sean C., Dubielzig, Richard R., Hatta, Masato, Katze, Michael G., Kawaoka, Yoshihiro, Suresh, M.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2010
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2951384/
https://ncbi.nlm.nih.gov/pubmed/20949022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1001139
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