Genetic Signatures in the Envelope Glycoproteins of HIV-1 that Associate with Broadly Neutralizing Antibodies

A steady increase in knowledge of the molecular and antigenic structure of the gp120 and gp41 HIV-1 envelope glycoproteins (Env) is yielding important new insights for vaccine design, but it has been difficult to translate this information to an immunogen that elicits broadly neutralizing antibodies...

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Main Authors: Gnanakaran, S., Daniels, Marcus G., Bhattacharya, Tanmoy, Lapedes, Alan S., Sethi, Anurag, Li, Ming, Tang, Haili, Greene, Kelli, Gao, Hongmei, Haynes, Barton F., Cohen, Myron S., Shaw, George M., Seaman, Michael S., Kumar, Amit, Gao, Feng, Montefiori, David C., Korber, Bette
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2010
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2951345/
https://ncbi.nlm.nih.gov/pubmed/20949103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000955
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