Genetic Signatures in the Envelope Glycoproteins of HIV-1 that Associate with Broadly Neutralizing Antibodies

A steady increase in knowledge of the molecular and antigenic structure of the gp120 and gp41 HIV-1 envelope glycoproteins (Env) is yielding important new insights for vaccine design, but it has been difficult to translate this information to an immunogen that elicits broadly neutralizing antibodies...

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Detalhes bibliográficos
Main Authors: Gnanakaran, S., Daniels, Marcus G., Bhattacharya, Tanmoy, Lapedes, Alan S., Sethi, Anurag, Li, Ming, Tang, Haili, Greene, Kelli, Gao, Hongmei, Haynes, Barton F., Cohen, Myron S., Shaw, George M., Seaman, Michael S., Kumar, Amit, Gao, Feng, Montefiori, David C., Korber, Bette
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2951345/
https://ncbi.nlm.nih.gov/pubmed/20949103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000955
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