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Growth Hormone (GH)-dependent Expression of a Natural Antisense Transcript Induces Zinc Finger E-box-binding Homeobox 2 (ZEB2) in the Glomerular Podocyte: A NOVEL ACTION OF GH WITH IMPLICATIONS FOR THE PATHOGENESIS OF DIABETIC NEPHROPATHY

Growth hormone (GH) excess results in structural and functional changes in the kidney and is implicated as a causative factor in the development of diabetic nephropathy (DN). Glomerular podocytes are the major barrier to the filtration of serum proteins, and altered podocyte function and/or reduced...

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Autori principali: Kumar, P. Anil, Kotlyarevska, Kateryna, Dejkhmaron, Prapai, Reddy, Gaddameedi R., Lu, Chunxia, Bhojani, Mahaveer S., Menon, Ram K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2951188/
https://ncbi.nlm.nih.gov/pubmed/20682777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.132332
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