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In vitro expression of NGN3 identifies RAB3B as the predominant Ras-associated GTP-binding protein 3 family member in human islets
Neurogenin 3 (NGN3) commits pancreatic progenitors to an islet cell fate. We have induced NGN3 expression and identified upregulation of the gene encoding the Ras-associated small molecular mass GTP-binding protein, RAB3B. RAB3B localised to the cytoplasm of human β-cells, both during the foetal per...
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Autors principals: | , , , , , , , , , |
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Format: | Artigo |
Idioma: | Inglês |
Publicat: |
BioScientifica
2010
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Matèries: | |
Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2951179/ https://ncbi.nlm.nih.gov/pubmed/20807725 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1677/JOE-10-0120 |
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