Anti-neutrophil elastase defense of the normal human respiratory epithelial surface provided by the secretory leukoprotease inhibitor.

Secretory leukoprotease inhibitor (SLPI), a 12-kD nonglycosylated serine antiprotease with a high capacity for inhibiting neutrophil elastase (NE), is produced by cells of mucosal surfaces including the human lung. The molar concentrations of SLPI in total respiratory tract epithelial lining fluid (...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Vogelmeier, C, Hubbard, R C, Fells, G A, Schnebli, H P, Thompson, R C, Fritz, H, Crystal, R G
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1991
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295108/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1671391/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115021
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