Anti-neutrophil elastase defense of the normal human respiratory epithelial surface provided by the secretory leukoprotease inhibitor.

Secretory leukoprotease inhibitor (SLPI), a 12-kD nonglycosylated serine antiprotease with a high capacity for inhibiting neutrophil elastase (NE), is produced by cells of mucosal surfaces including the human lung. The molar concentrations of SLPI in total respiratory tract epithelial lining fluid (...

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Pubblicato in:	J Clin Invest
Autori principali:	Vogelmeier, C, Hubbard, R C, Fells, G A, Schnebli, H P, Thompson, R C, Fritz, H, Crystal, R G
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1991
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295108/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1671391/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115021
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