Cargando...

Alport alloantibodies but not Goodpasture autoantibodies induce murine glomerulonephritis: Protection by quinary crosslinks locking cryptic α3(IV) collagen autoepitopes in vivo

The noncollagenous (NC1) domains of α3α4α5(IV) collagen in the glomerular basement membrane (GBM) are targets of Goodpasture autoantibodies or Alport post-transplant nephritis alloantibodies mediating rapidly progressive glomerulonephritis. Because the autoepitopes but not the alloepitopes become cr...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Luo, Wentian, Wang, Xu-Ping, Kashtan, Clifford E., Borza, Dorin-Bogdan
Formato: Artigo
Idioma:Inglês
Publicado: 2010
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2951005/
https://ncbi.nlm.nih.gov/pubmed/20709951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1001152
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!