Effects of Opioid Receptor Gene Variation on Targeted Nalmefene Treatment in Heavy Drinkers

BACKGROUND: Recent studies examining the moderating effects of polymorphic variation in opioid receptor genes have yielded conflicting results. We examined opioid receptor gene polymorphisms as moderators of the therapeutic effects of the opioid antagonist nalmefene. METHODS: Participants (n=272) we...

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Detalhes bibliográficos
Main Authors: Arias, Albert J., Armeli, Stephen, Gelernter, Joel, Covault, Jonathan, Kallio, Antero, Karhuvaara, Sakarai, Koivisto, Tiina, Mäkelä, Rauno, Kranzler, Henry R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950972/
https://ncbi.nlm.nih.gov/pubmed/18537939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1530-0277.2008.00735.x
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