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IL-21-deficiency Influences CD8 T Cell Quality and Recall Responses Following an Acute Viral Infection

CD4 T cells are principal producers of IL-21 and are often required for optimal CD8 T cell responses. Therefore, we investigated the importance of IL-21 in determining the phenotypic attributes, functional quality, and maintenance of anti-viral CD8 T cells following acute infection with the prototyp...

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Bibliographic Details
Main Authors: Yi, John S., Ingram, Jennifer T., Zajac, Allan J.
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950881/
https://ncbi.nlm.nih.gov/pubmed/20844201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1001032
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