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Modelling the Role of UCH-L1 on Protein Aggregation in Age-Related Neurodegeneration
Overexpression of the de-ubiquitinating enzyme UCH-L1 leads to inclusion formation in response to proteasome impairment. These inclusions contain components of the ubiquitin-proteasome system and α-synuclein confirming that the ubiquitin-proteasome system plays an important role in protein aggregati...
Gorde:
| Egile Nagusiak: | , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Public Library of Science
2010
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2950841/ https://ncbi.nlm.nih.gov/pubmed/20949132 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013175 |
| Etiketak: |
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