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Cartilage expression of a type II collagen mutation in an inherited form of osteoarthritis associated with a mild chondrodysplasia.

In a family who expressed severe dominantly inherited osteoarthritis, the underlying mutation was traced by genomic sequencing to a single base change which predicts an amino acid substitution of cysteine for arginine at residue 519 of the triple-helical domain of the type II collagen molecule (Ala-...

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Detaylı Bibliyografya
Yayımlandı:J Clin Invest
Asıl Yazarlar: Eyre, D R, Weis, M A, Moskowitz, R W
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 1991
Konular:
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295062/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1985108/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114994
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